Triamcinolone¶

Overview¶

Field	Detail
Drug class	Corticosteroid
Route	IM
Stock formulation	40 mg/mL
Reconstituted conc.	N/A (Ready to use)
Diluent	Nil
Storage	Room temperature; protect from light; do not freeze

Preparation¶

Before you start

Check the expiry date and vial integrity before opening. Label every syringe immediately after drawing up — never leave unlabelled syringes on the tray.

Equipment needed¶

1 × Triamcinolone 40 mg/mL vial
Normal saline (NS) — for SPT dilution and IDT dilutions
1 mL syringes × 4
25 G needles

Step 1 — Prepare the SPT solution (4 mg/mL — 1:10)¶

Draw up 1 mL of stock (40 mg/mL) into a syringe. Add 9 mL NS. Mix. (This is 4 mg/mL — 1:10).
Draw up 0.5–1 mL of this diluted solution (4 mg/mL) into a 1 mL syringe.
Label: "Triamcinolone SPT 4 mg/mL".

Step 2 — Prepare IDT dilutions¶

Prepare in this order, using a fresh syringe for each step.

IDT 0.04 mg/mL (1:1,000):
- Draw 0.1 mL of stock (40 mg/mL) into a 1 mL syringe. Add 0.9 mL NS. Mix. (This is 4 mg/mL — 1:10).
- Draw 0.1 mL of this 4 mg/mL into a new 1 mL syringe. Add 0.9 mL NS. Mix. (This is 0.04 mg/mL — 1:1,000).
- Label: "Triamcinolone IDT 0.04 mg/mL".
IDT 0.4 mg/mL (1:100):
- Draw 0.1 mL of the 4 mg/mL solution prepared above into a new 1 mL syringe. Add 0.9 mL NS. Mix. (This is 0.4 mg/mL — 1:100).
- Label: "Triamcinolone IDT 0.4 mg/mL".
IDT 4 mg/mL (1:10):
- Draw 0.1 mL of stock (40 mg/mL) into a 1 mL syringe. Add 0.9 mL NS. Mix. (This is 4 mg/mL — 1:10).
- Label: "Triamcinolone IDT 4 mg/mL".

Skin prick test (SPT)¶

Reagent	Concentration
Test solution	1:10 (4 mg/mL)
Positive control	Histamine 10 mg/mL
Negative control	Normal saline

Interpretation: Wheal ≥3 mm vs negative control = positive.

Intradermal test (IDT)¶

Dilution series¶

Step	Dilution	Concentration	Preparation
1	1:1,000	0.04 mg/mL	0.1 mL of 4 mg/mL + 0.9 mL NS
2	1:100	0.4 mg/mL	0.1 mL of 40 mg/mL + 0.9 mL NS
3	1:10	4 mg/mL	0.1 mL of 40 mg/mL + 0.9 mL NS

Inject: 0.05 mL intradermal. Read at 15–20 minutes.