Rosuvastatin (Crestor)¶
Overview¶
| Field | Detail |
|---|---|
| Drug class | HMG-CoA reductase inhibitor (Statin) |
| Formulation | 10 mg tablets (Common) |
| Reconstituted conc. | N/A (Oral) |
| Storage | Room temp |
Preparation (Desensitisation)¶
Protocol Context
Rosuvastatin desensitisation is typically performed for patients with a history of non-severe hypersensitivity who require statin therapy. This protocol uses standard 10 mg tablets.
Equipment needed¶
- 3 × Rosuvastatin 10 mg tablets
- Water for swallowing
- Observation chart
Desensitisation Protocol¶
Dosing Schedule¶
| Step | Dose | Formulation | Cumulative Dose |
|---|---|---|---|
| 1 | 10 mg | 1 × Tablet | 10 mg |
| 2 | 10 mg | 1 × Tablet | 20 mg |
| 3 | 10 mg | 1 × Tablet | 30 mg |
Interval: 30 minutes between doses. Total Dose: 30 mg.
Post-Protocol
If the desensitisation is successful, the patient should continue their prescribed daily dose (e.g., 10 mg or 20 mg) starting the following day without interruption.
Notes¶
- Monitor for signs of hypersensitivity (rash, itch, respiratory distress) between steps.
- This protocol is specific for immediate-type reactions. For delayed muscle symptoms (SAMS), a different clinical approach is required.